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Pilocarpine is a muscarinic agonist that primarily stimulates the sphincter pupillae and ciliary muscle of the eye, leading to miosis (constriction of the pupil) and accommodation (focusing ability). Its main indications primarily involve the management of conditions related to pupil response and intraocular pressure.

The use of Pilocarpine in the diagnosis of Adie's tonic pupil and for assessing cranial nerve III (oculomotor nerve) palsies is due to its ability to elicit a strong pupillary constriction response in these specific conditions. In the case of Adie's pupil, for example, Pilocarpine helps differentiate between a dilated pupil due to a sympathetic dysfunction or a failure of the parasympathetic system.

Additionally, Pilocarpine is utilized prior to laser peripheral iridotomy (LPI) surgery to facilitate a reduction in intraocular pressure and aid in the reshaping of the anterior chamber. This makes the procedure safer and more effective.

However, while Pilocarpine has potential applications in various ocular disorders, it is not a primary treatment for Myasthenia Gravis (MG). The treatment of MG typically focuses on anticholinesterase medications such as pyr